Top Definition
1. A gesture of confirmation.
2. Another way of saying "okay".
3. In good condition.
Used by Mr. Saturn in the SNES game Earthbound.

Can you get me that book over there?

"Are you kay-o?"
by David S May 17, 2006
Hiding cocaine in Mayonaisye Jars and being okay with it.
Thug 1: Did you just hide your Yayo in your Mayo?
Thug 2: yeah it's called Kayo
by Dus10_L January 02, 2015
Someone who calls a woman "whore" or "slut" because he knows she is out of his league and that she would mock him for the size of his penis.
That poor dude is such a kayos he couldn't get water from the town pump.
by Citizen Kayos March 06, 2008
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