Top definition
Doing irreparable harm to your own best interest through the consequences of your own actions.
(1)Bill Clinton's relationship with Monica turned out to be karmacide.
(2) Hey man, did you hear that Max committed karmacide when he went on a drunken spending spree and over-spent his credit card by $10,000.
(3) I am asking Kelly to marry me, hope it does not turn out to be karmacide.
by Exigent Mind January 07, 2011
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