to be tweaked out of one's mind without the use of any drugs, alcohol or medication.
man, this guy isnt even high... hes been jamesin' it the whole time!
(1)an act of utter disregard for the rules of society. complete and absolute stupidity without the aid of paraphenalia.
1. Dude, that guy is totally warmerdaming on that chick.
2. I think tonight it's time to pull a James.