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1.
short form of "it's ok"
"OMG, someone stole our cat!!!"
"Isok, we can get a new one."
by DinoRick December 24, 2013
 
2.
Is iSOK capable of definition? iSOK is moody. The iSOK was a notion of angst and sexual innuendo cherished by the Miklaseds of Central Asia. He is undoubtedly your mother. "Keep away from Tyrants." - iSOK warning label. He slices, he dices, and can own your ass in Snood, as well as everything else in general. Yay iSOK.
"Drat that dratted iSOK. I can trace all of my problems back to two things: iSOK and the sun."
by Sed Kimique November 06, 2003