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1.
noun.

A mental disorder which skews a persons perception of their place, importance, or belonging within a group of their friends or colleagues. Usually this is a result of overexposure, constant suggestions of terrible ideas or advice, and general dislike of the individual.

Signs of this include speaking to groups of people who are not paying attention, not getting invited to social gatherings or events, and constant feelings of uselessness.
Ex. 1:
Todd- Hey what's the deal with Mark? He never seems to shut up anymore.

Dwayne- Oh yeah, he's just suffering from irreleventia, he just hasn't realized it yet.

Ex. 2:
Tammy- I don't get it Sue, why won't Brian call me back?

Vicky- Well Tammy, word on the street is after you put out, he diagnosed you with irreleventia.

Tammy- What's that?

Vicky- Beats me, but it looks like you're not going out tonight.
by SnooksOnFire April 01, 2009