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1.
Home cheese is synonymous with homie, home boy, home skillet, home slice and the seldom referenced home piece. All of these expressions are terms of endearment--in an urban context--and are meant to demonstrate affection and either familiarity or at least a similarity of circumstances. Home cheese dates from at least the late 1980s' early hip hop scene. It, along with home skillet was usually said in a somewhat ironic manner, i.e. it was purposely absurd.
Yo, what up home cheese? What be the haps?
by Hooper X June 01, 2006
19 3
 
2.
one of your best friends
you run into a friend and say "Whuddup, Homecheese!"
by Erik Z. April 17, 2005
13 2
 
3.
A made up term used by Midwestern folks. Generally used when stumbling over words to cover up a general lack of cool names.
"Hey, I like that jacket... Home Cheese!"
by TheCheesiest September 13, 2011
0 1
 
4.
A lazy little bastard that does nothing.
Get off the couch home cheese!!!
by nickkko June 09, 2005
5 12