A word used intermittently in approximately every other sentence of medical school facts indicating that it is very important. In the popular pathology review series called "Pathoma", it's used at the end of sentences in place of a period.
It's important to know that this entire textbook will be high yield.

"Yeah right John, there's no way. I'm about to go high yield on this 12 pack of Hamm's instead".
by HighYieldHamms November 8, 2013
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Work/activity that involves minimal input to achieve the maximal output in the lowest possible time
Becks Triad - Muffled heart sounds, raised JVP and hypotension is a high yield fact for cardiac tamponade

starry sky is a high yield fact for burkitts lymphoma
by HighYielder May 30, 2011
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Providing a lot of pleasure, satisfaction, or utility
Damnnnn Taco Bell’s cinnamon treats are v high yield.
by NJrocks993 June 8, 2019
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