Although not identified as gender specific, the term "High Mileage" in a slang context is generally defined as any woman who is either known or perceived to have been with numerous sexual partners.

The term may also be seen or written as High-Mileage.
Thomas was becoming interested in Maxine but decided against it upon hearing she had a reputation for being a high mileage girl.
by Who 'Dis? Who 'Dat? February 12, 2019
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Term used in reference towards a chick that has been more than likely around the world and back in the slut/skank/whore department...which has taken a total on her physical condition either down or upstairs but usually both.
Jack: Yo man check out that blonde hotty gettin all crazy over there, you think i could get that?

Blake: Dude wtf is wrong with you man?! Look at all that caked up makeup...don't be fooled by that worn out trash, she's gotta be a total "High Mileage Ho."

Jack: Good call man, she does seem a little worn around the edges, keep my drunk ass away from that tonight.

Blake: Likewise.
by servinthatruth March 24, 2010
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