Slang for pussy- especially one that ejaculates, queefs, or pops out shitty children excessively.
"Looking down the barrel of that chick's guava-cannon is like staring at the distended mouth of a palsy patient."

"Swear t'Jesus- I was lyin' on the bed after we fucked, and she climbed over me to use the bathroom. All'a sudden her guava-cannon fires off, and now I gots the chunkies in mah chest hair."
by Abdallah Price November 04, 2011

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