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1. get out of Dodge
To leave(refers to dodge city, Kansas, a catchphrase from western entertainment)
I don't like the looks of this place. It's time to get out of Dodge.
2. get out of dodge
Leave a bad or dangerous (or both!) situation.
After loudly opining in the crowded bar that "only Steers and Queers come from Texas" Jim-Bob decided that it was time to get out of Dodge.