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A fumble six is the occurrence in American Football when the offensive player fumbles the ball, and a defensive player picks up the ball and returns it for a touchdown. Hence the six, for a touchdown is worth six points.
Ex 1: Dude I destroyed you in Madden 12! I got like 5 fumble sixes!

Ex 2: The highlight of the player's career was when he got a fumble six.
by FUMBLE SIX! March 03, 2012
4 1