look up any word, like the eiffel tower:
 
1.
When you book it after finishing sex.
"Well, I hate to fuck and run, but I've got to get home. Bye."
by Marsha H January 01, 2007
 
2.
....basically a one night stand, hooking up with some chick for casual, no strings attached sex, then dumpin her in the mornin
soo important, that you don't exchange personal info...unless you intented for her to stalk you.
Dude, i just had this fuck and run with some girl i picked up at the club last night
by TreeBo January 22, 2008