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fo shizzle mah nizzle 

Fo(Fo) sho(Shizzle) ma(mah) nigga(nizzle)
and to the white man that means
For(fo) Sure(shizzle) my(mah) African American (Nizzle)
Old Lady: fo shizzle ma nizzle
Snoop: for your information Nizzle does not mean neighbor

Fo shizzle mah nizzle 

Ebonic rhyming of "For sure, my nigger!"
Form of agreement among blacks.
Brutha #1: "Let's go get some fine boo-TAY!"
Brutha #2: "Fo shizzle mah nizzle!"

fo shizzle mah nizzle 

"fo shizzle mah nizzle" is a bastardization of "fo sho mah nigga" which is a bastardization of "for sure my nigger" which is a bastardization of "i concur with you wholeheartidly my african american brother"
ghetto person 1- "dat gurl at dat bbq wuz wak son"
ghetto person 2- "fo shizzle mah nizzle!"
me- you're lame.

fo' shizzle mah nizzle 

Damn right, my African American friend/brother.
For sure, mah nigga.
Correct and right, my Afro-American friend.
Snoop:''That vanilla face sure thinks he is the shizzle''
Dre:''Fo' shizzle mah nizzle''

Snoop:''Eminem is a puff''
Dre:''....Fo' shizzle mah nizzle''

Fo shizzle mah nizzle 

You wanna play some b-ball?
Fo shizzle mah nizzle
Fo shizzle mah nizzle by Bj February 17, 2003

Fo shizzle mah nizzle 

Slang for 'For Real My Nigga'
You is fo shizzle mah nizzle wizzle
Fo shizzle mah nizzle by Paul April 27, 2004