When you or someone else has an extra chromosome causing them to be retarded
Bro I think Melisa from the Voice has an extra chromie
by PPSOFTBrynanna May 17, 2019
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Person with Down Syndrome, due to the fact the condition is caused by a person being born with 47 chromosomes instead of 46.
That guy with Down Syndrome is my Homie with an extra chromie.
by Golden Hawk April 13, 2023
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People who have extra chromosomes and are best friends. "Chromie" referring to chromosome and "homie"s referring to " people who are good friends and would die for each other".
People who have extra chromosomes and are friends are considered extra chromie homies. Yesterday, John and I went into the extra chromie homie room by accident.
by B4dg3r January 13, 2017
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That one dude who you know has your back when that autism strikes.
Autistic Child #1: I'm gonna shoot up the school
Autistic Child #1: You cool though.
Me: You my homie with an extra chromie man.
by Phiriz January 31, 2018
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