A testicle infused with estrogen, or born of estrogen, causing a man to be a lot more feminine, passive, or just generally pathetic.
First guy: Dude, you've liked her for years, just man-up and tell her!
Second guy: I can't man. I've got an estroticle and it's preventing me from doing anything manly.
Second guy: I can't man. I've got an estroticle and it's preventing me from doing anything manly.
by I'mma Venitian February 11, 2010