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ego death 

The perceived loss of boundaries between self and environment

a possible effect of LSD, special K, shrooms, and mescaline among others
My ego death completely changed my life.
ego death by Sourbs March 21, 2007
Related Words

Ego Death 

A complete loss of ego and self-worth, generally occuring during the use of psychedelics. (ie. LSD, Marijuana, Ketamine, mushrooms, salvia)
My ego death last night was harsh, i thought i was worthless, i questioned my life all together.
Ego Death by ConnorM June 11, 2008

ego death 

when someone roasts you so hard that your ego just dies on the spot.
- What’s up with Chad?
~ Brad roasted him so hard he won’t talk to anyone. I think he’s going through ego death.
ego death by 201275 October 15, 2018

Major Ego Death 

Major Ego Death (MDE) is when someone's ego collapses so hard, it can no longer repair itself.
Bob had a Major Ego Death after posting on r/RoastMe. Talk about no self respect.
Major Ego Death by Bloobdy October 10, 2025