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1.
To insult through the means of email or other internet communication devices; to send a picture of a fist or striking hand along with a description of the cause of the e-smack.
"Has anyone ever told you you look like Bob Saget off of Full House?"
"I ought to e-smack you for that one!"
by Buddy Holly March 14, 2005
 
2.
If a person you are talking to on the internet has said something dumb or stupid then they should smack themselves 5 times to equal one of your smacks since you are not there to smack them.
Fat Girl: I would like to get to know you some time.
Kyle: Hell naw you need to e-smack yourself.
by J.T September 07, 2005