Duff you up means punch you up
Bro ima duff you up: said girl
by MT15 June 5, 2020
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A person who was a duff in their past and is now a hot glown up masterpiece
Guy 1: Damn heathers a come up duff!
Guy 2: Yah she used to be really ugly but now I really wanna date her
by Em's definitions August 14, 2017
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