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1.
Someone who does nothing but drugs, and often isn't too intelligent.

Comes from the Archie Comics character Jughead and the word drug.
Person: Wooaah man, I'm tripping OUT!
Passerby: Shut your trap, Drughead.
by CalmandOdd November 19, 2008
13 2
 
2.
the word that not-so-smart people use to mean someone who is on drug (basically someone combined "druggie" and "pothead")
i'm not dumb enough to be a drughead like you.
by your mom October 07, 2003
14 14