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dansyndrome 

an awful disease where a man gets very hot women but they tend to be too stupid to talk to. Its very sad for the infected but it is great for the kids friends because they have someone new to jerk to
Wow daniel's girl lizzy is sexy. Shes probably stupid though, daniel has dansyndrome
dansyndrome by moviegoer1239 December 6, 2010

Downsyndromatic 

Boogaloo is hella downsyndromatic
Downsyndromatic by JooxTheGreat September 22, 2011

Domsyndrome 

A medical condition originated from the name of a self-entitled prick. The person suffering from this condition begins to show hyper-selfish behavior, often reality seems blurred to them and the being hallucinating into their own world where everything revolves around them and every person does what they tell them to do.
"Oh, he keeps arguing on the fact with no reasoning though specialists have explained it to him, Domsyndrome is really spreading fast"

"He started talking about how he created the seven wonders, sad how Domsyndrome has taken over him"
Domsyndrome by notrachit May 19, 2018

Downsyndric 

To be a total dumb ass or life falure without being born with downsyndrome.
When in the not knowing or not knoledgeable of how things are done in the hood.
May be the cause of to much drinkage of haterade.
Jordan: Brooklyn what is the point of life?
Brooklyn: ummmmmmmmmmm idk
to live?
Jordan: That is a very downsyndric thing to say you niglet.

"One day while purchasing KFC in the Line"
Jordan: Brooklyn do you think Africian Americans are nice people?

Brooklyn: No I hate NAGGERS, they smell, dont do enough work, make things uncomfortable and suck in the American government
Jordan: WOW Omg brooklyn that is so downsyndric, you say that in their hood Dumb ginger!!!!!!
Downsyndric by Wettpussy July 14, 2010

downsyndrick 

Mike: "lets go play pretend!"
Joe: "Shut up Mike, you're downsyndrick!"

Downsyndromistic 

A word you use for someone who is very retarded
Tardo: yo I think this girl likes me!
Me: what are you downsyndromistic?

downsyndrick 

downsyndrick
To have autism and down syndrome at the same time.

Example:

Mike: "Lets pick flowers!"
Joe: "You must be a downsyndrick retard, get out of my life!"