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how do you do? 

Somewhat archaic greeting. Was popular in England in polite society before the 50s.

The phrase is somthing of a non-sequiter - if read as written there's only half a verb, because one usualy does somthing rather than just does. The question could be construed as 'doing' your girlfriend or wife, but the intent is not to open a discussion on sexual acts, but rather to greet.
Jack: How do you do?
Jill: I am well Jack, and yourself?
how do you do? by Swamp Ig December 2, 2005

how you do dis? 

A slang term that implies confusion and befuddlement. Often used when you have not been paying attention and you have to do a worksheet or test. This expression usually pisses people off.
"This worksheet is on standard deviation; how you do dis?"
how you do dis? by Chunky Reddy January 3, 2009

Tucson How Do You Do

When you kiss your friend’s dad while he’s on the toilet
Bracken: Oh yeah my dad is in the bathroom
Christian: Well in that case I’ll give him a Tucson How Do You Do!

how do you do 

Just askin' how do you do.
how do you do by Hercolena Oliver August 23, 2009

how-do-you-do

(Noun) a prudish way of saying penis, used by Dr. Elliot Reid due to her aversion to using proper terms for genitalia.
Never let a man put his dirty how-do-you-do into your bajingo!
how-do-you-do by Dr. Reid February 27, 2008

how do you do homework 

why are u searching this on here and not google?
person 1: how do you do homework?
person 2: pay attention in class homie