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1) A frequent user of the drug DXM (dex), which comes in cough syrup. If ingested in high amounts, DXM can produce hallucinogens and euphoric feelings.

2) Used in reference to a person who is generally spaced out, or oblivious to his or her surroundings.
1) My friend is such a dexhead! He just bought two more bottles of nyquil, and he's tripping on the shit right now!

2) That kid on my bus was just staring out the window when Ashley was trying to talk to him. What a dexhead.
dexhead by joe February 12, 2004
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A person who frequently abuses the drug Dextromethorphan.
I am a Dexhead.
Dexhead by Aces High November 30, 2003
Related Words
A person stuck in the 80's...may have a mullet, tight jeans, sometimes pegged, comb in back pocket, listens to Def Leppard, and drinks Mountain Dew (in a glass bottle if available). Most often seen driving an old Camaro or Firebird. Watches Nascar and drinks cheap beer. The female form still has "mall hair" after all these years, curses like sailor, and still owns a Warrant CD.
"Look at all the dewheads in line for Poison tickets!"
Dewhead by Phil Hitt July 24, 2003
An alternative spelling of behead. It means to chop/cut someones head off.
The king had the criminal deheaded for his crimes.
Dehead by KaBob799 February 1, 2009
A fan of DEFTONES...A mostly honorable nickname actually!
Evan: What is the best band; Incubus or Deftones huhh?

Jones: How dare you mention the mighty Def´ in the same sentence as that lamecore popfunk band of wankster?

Evan: You are such a Defhead...

Jones: Hellll Yeahhhhhhhhhh! I´m buying the next round!

Evan: ....*sigh*....
Defhead by Tankred February 23, 2011

dexheads 

All those crazy kids in grade school.
Hey, man! Those dexheads are robotripping again!!
Eric's mom used to be a dexhead; now she can't recall where she lived.
dexheads by The Red November 1, 2007

Deheadify 

A synonym to decapitate, though it sounds far more awesome.

Originally said by Dane Boe in the video "Plants vs Zombies #42: Double Sunflower!"
I'm going to deheadify you, you mofo!
Deheadify by Wetterl May 26, 2011