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1. An awesome person. Name could be used to describe others who are of equal awesomeness, except none exist.

2. A drink comprised of half jack daniels honey, half cherry vodka, with a splash of lime juice.
I didn't know what drink to order, so I ordered a Despina, which I thought would make me as awesome as Despina, but sadly it wasn't enough.

"I'm just fucking awesome."- actual quote from Despina herself
Despina by Shorter Story May 24, 2013
Related Words
One of the most beautiful people in this earth. She’s a wild spirt but is very cautious. She has a heart of gold ❤️.She will make your day no matter wha. She is a unique person who you can count on 24/7 .She is someone you want to adore, and get to know
Destiana is everything I wanted I’m one lucky guy
destiana by Woahxesme September 25, 2018
Despina means "Lady" in greek but it's also as a name. Despina is a beauty with dark brown hair, gorgeous eyes and an amazing personality. She's the type of person to eat everything that catches her sight but not gain weight. She loves her friends and she's really outgoing. She is quite the attention seeking type and for that she gets scolded sometimes but other than that, she's a perfect human being.
Girl:Omg despina is so pretty! I wish I had her body! >.<
Boy: Ikr she's gorgeous!
Despina by Dabdabz December 31, 2017
Greek name for "Lady". Commonly interchanged with the virgin mary's name.. the nameday is August 15th. Nicknames for Despina are Des, Desi, Debbie, Despinoula, Despinaki.
Despina Kats is the coolest ever, and Despina Vandi is a famous pop singer.
despina by Despinoula April 25, 2008

despanxed 

the less desirable state of a portly female after removing her fat hiding undergarment
That fly girl at the club turned into Star Jones after she despanxed in me and my uncles apartment
despanxed by 2012 Cowboy March 9, 2009
A lesbian who uses Debian
I was a desbian until I moved to Arch