look up any word, like pussy:
Defrig is a word used to tell others to calm down, take a chill pill, stop being an idiot, stop getting all up in your grill etc.
If an individual is taking a spaz at you just simply say "Man, defrig" and everything should be alright.

Or if something is bugging you.... "Holy heck! My computer won't defrig"

by kateroo January 25, 2006