Top definition
1) a condition in which you can not escape the ability to say the most awkward thing at the most awkward moments

2) a person who commonly ruins their own dignity by saying or doing something awkward constantly
1) oh man, i sure feel sorry that he has defren. he used to be kinda cool.

2) that dude is such a defren, why can't he just act cool for one day?
by bsaxbuc March 21, 2007
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