Any time ejaculate ends up where it's not supposed to be.
"Man last night I was jacking off to porn and I cumfumbled all over my keyboard."

"I need to go get plan B. Mike accidently came inside me. Terrible cumfumble!"
by keatsway July 23, 2008
The phenomenon that occurs when - right at the moment of climax - your grandma calls. Essentially, any action that ruins an imminent orgasm.

Can also be called the cumble fumble or simply cumble.
Guy - "Oh baby, I'm gonna cum."
Girl - "Fill my sweet poonani with you jizzum, please!"
Guy - "Urm.. I think you just cum fumbled me."
by conbonjovi December 09, 2009

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