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commander cuckoo bananas 

Homer Simpson's nickname for *, AWOL George, Shrub, Miserable Failure, Cimpy McCokespoon, Dumbya, etc. (George W Bush)
Marge: Bart, I love you, but sometimes I don’t love your choices. (sigh) Now we have to find another school for you.

Homer: Yeah, and if you get kicked out of that one you’re going straight in the army where you’ll be sent straight to America’s latest military quagmire. Where will it be? North Korea? Iran? Anything’s possible with Commander Cuckoo-Bananas in charge.

cuckoo banannas 

Made famous by Manny on Degrassi its used to ask someone "have you lost it?","are you insane?" or "crazy"
"omg,you asked that loser out,have you gone cuckoo banannas?!"

Cuckoo Bananas

a saying used to call somebody an extreme version of crazy
She ran a mile on a whim. Her friends said "She is Cuckoo Bananas."

cuckoo bananas

its a catch phrase manny santos from degrassi TNG uses alot
it means crazy in a cool, girlish, fun way
hello cuckoo bananas, im gonna go cuckoo bananas
cuckoo bananas by DR. JT YORKE January 7, 2010

CucKoo Bananas

cuckoo bananas is an expression usually said when something goes wrong or you make a certain mistake. Or simply just say the word because its fun saying it :P
"omg thats SO cuckoo bananas!"
or simply
"Holy crap im gonna go cuckoo bananas!"
CucKoo Bananas by tHAT_d0rK101 November 28, 2007