Being hit on by a member of the same sex. The term cruz'd comes from both cruising for sex and the implication that the cruz'ee might have met the cruz'er on a gay cruise some where.
Gay Man: Didn't I see you on that cruise out of P-town?
Straight Man: Nope.
GM: Quel Dommage. (walks away)
Straight Man #2: Dude, you've been cruz'd!!