A genetic thread of human dna.
usually used in insult
YOU'RE MISSING A CHROMOSONE/CHROMOSONES YOU MONGOLOID CUNT
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spelling of y chromosome by an illiterate moron
she flunked her biology mid-term and even spelled y chromosome wrong. That Twat is such a twit that she wrote down y chromosone.
by AdamanEve October 10, 2005
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Refers to the ability of men to listen to women without hearing anything they say. Generally used by one woman to another as an excuse for losing track of a uninteresting monologue that suddenly requires input.
"So if he said that he meant to say that he didn't say it, but he did say it, but because I didn't hear it, I can't really hold it against him. What do you think?"

"Huh? Damn, girl, I'm sorry. I just went all XY chromosone for a minute."
by SuperMilkChan February 21, 2007
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Refers to the ability of men to listen to women without hearing anything they say. Generally used by one woman to another as an excuse for losing track of a uninteresting monologue that suddenly requires input.
"So if he said that he meant to say that he didn't say it, but he did say it, but because I didn't hear it, I can't really hold it against him. What do you think?"

"Huh? Damn, girl, I'm sorry. I just went all XY chromosone for a minute."
by SuperMilkChan March 5, 2007
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that would be the birth defect that brings us those boys... just kidding.. i love guys!
guys have y chromosones and girls have x
by lauren November 16, 2004
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Refers to the ability of men to listen to women without hearing anything they say. Generally used by one woman to another as an excuse for losing track of a uninteresting monologue that suddenly requires input.
"So if he said that he meant to say that he didn't say it, but he did say it, but because I didn't hear it, I can't really hold it against him. What do you think?"

"Huh? Damn, girl, I'm sorry. I just went all XY chromosone for a minute."
by SuperMilkChan February 25, 2007
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Something no one seems to have anymore.
"hello class today were going to talk about this shitty x chromosone which none of you have anymore you dumb fucks."
by Dr Death 2.0 February 28, 2016
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