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1.
To beat up a person so hard, that they would not be able to walk after it, just like Charlie Murphy did with Rick James...
Heidaros: Miranus, I'm going to charliemurpylize you bitch.
Miranus: No!, forgive me master, I will obey hereafter.

or

Man #1: Dude, that guy really needs to be charliemurphylized
Man #2: Yea bro, lets charliemurphylize his ass!
by Rasheed Rahman Al-suedi January 04, 2011