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1.
In a message board, when someone breaks a chain of people repeating the same phrase, it is considered a c-c-c-combo breaker.
In a topic on a message board...

n00b102: What is Doom?
1337Guy: It's a computer game.
nubkiller: It's a computer game.
sexigurl: It's a computer game.
1337one: It's a game from id software.

Moth389:C-C-C-COMBO BREAKER!!!
by DistinctlyBritish August 09, 2004
 
2.
It came from killer instinct in which you could stop someones combo right then and there hense why it is called a combo breaker which the announcer pronounces it C-C-C-C-Combo Breaker
Play KI you shall see
by Dynamo October 08, 2004
 
3.
It's an expression to say that someone changed something that had been repeated.

A bunch of white US presidents until Barack Obama broke repeated combo.

C-C-C-COMBO BREAKER!
by eleZeta November 05, 2008
 
4.
Barack Obama
Presidents: white white white white white white white white white white white white white white white white white white white white white white white white white white white white white white white white white white white white white white white white white white white BLACK

C C C COMBO BREAKER!
by TheRival November 01, 2009
 
5.
Breaking the combo on a comment board or group IM.
Anonymous: Now, this is a story all about how
Anonymous: My life got flipped-turned upside down
Anonymous: And I liked to take a minute
Anonymous: Just sit right there
Anonymous: I'll tell you how I became the prince of a town called Bel Air
Anonymous: In west Philadelphia born and raised
Anonymous: On the playground was where I spent most of my days
Anonymous: Chillin' out maxin' relaxin' all cool
Anonymous: And all shootin some b-ball outside of the school
Anonymous: When a couple of guys
Anonymous: Who were up to no good
Anonymous: C-C-C-COMBO BREAKER!
Anonymous: Asshat.

Anonymous: Old Godzilla was hoppin' around
Anonymous: Tokyo city like a big playground
Anonymous: When suddenly Batman burst from the shade
Anonymous: And hit Godzilla with a bat grenade
Anonymous: Godzilla got pissed and began to attack
Anonymous: But didn't expect to be blocked by Shaq
Anonymous: Who proceeded to open up a can of Shaq-fu
Anonymous: AND I JUST C-C-C-COMBO BROKE YOU.
by MegamanTTEX January 01, 2010
 
6.
When Barack Obama changes up a history of white presidents by being black and being the 44th President.
Dude 1: Yo, Barack Obama just got elected President by stomping John McCain!

Dude 2: C-C-C COMBO BREAKER!!!!!
by DeazKnights November 05, 2008