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1.
Otherwise known as "alopecia"
Buttercream is a word used to describe a man (or woman) who is 100% hairless (no scalp hair, eyebrows, facial hair, body hair, pubic hair, etc)
"Haha, check out that guy, not a single hair on his body, He's a total Buttercream."
by GonorrheaJoe April 15, 2008
 
2.
when you get beat up nice
billy bob got punched in the face by officer dave; got beat up like butter cream
by tekz August 07, 2006