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Bracket Flu 

Bracket Flu: A disease caused by ten men and an air-filled rubber ball that becomes widespread in the United States the 3rd weekend of March. The disease has been known to be terrible duing years of widespread upsets and buzzer beaters.

Symptoms: Fatigue, irritability, confusion, dizzyness, nausea

Severe cases have been known to cause depression causing many to stay home from work/school on Monday after the first and second rounds are complete.

The Only Cure: A minimum of one Buzzer Beater the following weekend.
Jim caught bracket flu after Ohio U beat Georgetown in 2010. He didn't return to work for a full week.
Bracket Flu by valleymd March 18, 2010
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bracketfucked 

To have your entry in an office pool or bracket, particularly for the NCAA men's basketball tournament, become worthless because one of your teams lost much earlier than anticipated.
That Georgetown game completely bracketfucked me. I had them winning the whole tournament, so I have no chance of winning money now.
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