its when your drunk and your with a bunch of loud mouth girls who are drunk and you say drink up bitches hoping they will get so drunk they will pass out and be quiet
i am at a concert and the girls would rather talk than watch the concert so you lift ur drink up and say drink up bitches
by julie cavender July 3, 2011
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Like the mob word "Stand up guy" A stand up bitch is a endearing term to describe a woman or group women with whom a man acciocate's with and has developed a solid friendship with them.
(DeeJay Don Juan) said right before his debut broadcast on SiriusXm radio...'Yo - I wanna give a shot out to A Stand up bitch All home girls from around my way! You know who you are!' You are A stand up bitch and without A Stand up bitch in my life, I wouldn't be here today. Thank you for all your kind words and support God bless!'
by SpinDriver March 22, 2012
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1. Used to tell a person to "shut the fuck up" and call them a bitch in simple three word phrase. This use of the word commonly includes the use of the middle finger.

2. Also used to end a conversation or when parting ways. Can be replaced with "goodbye" "see ya later" and "hasta la viesta, baby."
1. "Graham, you need to do your homework right now!"

"hey mom, guess what. Fuck up, Bitch" *flips off mom*

2. "Hey man, thanks for the ride."

"Oh it was no problem dude."

"Alright, well I'll see you later."

"Yep. Fuck up, bitch."
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Used to inquire another as to their response to what can usually be referred to as a verbal ass-kicking.
"Your mom is so stupid, when your dad said it was chilly outside, she ran outside with a spoon. yeaahh!! what YOU got? roll up, bitch!"
by Danny Peck January 21, 2004
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Used specifically before getting pumped up for a sports game, it refers to how much we the home team is bringing and that the other team better {up the ante} or we will make them eat dirt like good little bitches.
By Itself (yell it really loud) "Ante Up Bitch"
by Sean "Yo Motha" C'Dog June 24, 2005
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sssssssssss ssssssssssss asssssssssss
sssssssssssssssssssssssssssssss s s
by billy bob September 2, 2004
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When a female is being maddd retarded.
Girl I’m about to go Rob this nigga.

Girl SHIT UP BITCH
by Strawberry504 August 13, 2018
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