Top Definition
A very large shit usually taken after eating any type of food that is shit-inducing. A bathroom nuke is the deadliest of all shits in that when a person has a bathroom nuke the whole area must be decontaminated for the next 48 hours.
I went to the bathroom today,opened a stall,and there was a bathroom nuke everywhere.
by Wetback Joe May 24, 2010

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