Top definition
1. What happens to your ass the morning after a night of binge drinking.

2. General illness involving one's ass.
1) Dude, I've got one serious case of assthrax.

2) Man, my bum is on fire. It must be the assthrax.

3) Chipotle is rowdy. I think I've got the assthrax.
by Morning News February 12, 2008
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