Top Definition
Recognised medical condition arising from a period of prolonged cohabitation with a recently exed spouse or domestic partner, whereby hitherto amicable separations risk lurching into loathing and recriminations due to sudden lack of shared interests and/or future aspirations, see also ex stress.
Why's Dave being such a douche at work?

Oh, he was diagnosed with amicable fatigue - give him ten days and then go for a beer with him.
by 7PASV June 30, 2014
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