Top Definition
The process of drinking more alcohol while at the same time taking a piss, therefore refilling the emptiness left in your body from your pee.

In medicine, alcoholysis (from "alcohol", meaning liquid of the gods, "alcohol", meaning alcohol (duh), and "lysis", meaning loosening) is a process for removing alcohol from the system while introducing more at the same time, and is primarily used to replace the alcohol lost from your system while taking a piss, to adequately maintain the proper level of awesomeness in your body, to continue your epic night which you won't remember anyways.
In order to stay in the proper party fashion, I was forced to undergo an alcoholysis.

Guy 1: Hey 2, are you done for the night?

Guy 2: Uhhh.. (burp) Nahh mann, I'm jus' gonna get an alcoholysis done, to (burp) refresh the tank.
by Eddy A. Poe October 07, 2011

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