to be extremely high off of cocaine.
1: you o.k. man?

2:YEA DUDE TOTALLY, ALL YAKED UP RIGHT NOW

1:ummm... that explains the yelling. you have fun with that, just leave me out of it.
by atroxtyronebiggums November 21, 2011
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A phrase used to divert and meander away from the original talking point in a conversation for humorous/comic relief purposes. It intentionally misleads the other participant into believing you've stumbled upon a new concept when in fact, it's yake up! Yake up can be used in all kinds of conversations but it gets better with regular usage. It's fun to weave yake up into normal conversations and try and obscure it in new and exciting ways.
Person 1: "I am feeling so confused about this subject recently..."
Person 2: "I believe it could be closely related to a new burgeoning new field of study..."
Person 1: "Oh yeah? What field would that be?"
Person 2: "Yake up."
Person 1: "You got me again!"
by _Blode September 17, 2018
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