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1.
YSU
can refer to Youngstown State University, a state university in Youngstown, Ohio; or, in slang terminology "You Screwed Up", commonly used by residents of Northeast Ohio in reference to someone who attempts to leave the area for college but eventually attends the University
"I wanted to attend Kent State, but now i'm stuck going to YSU."
by Smiley McGiggles August 27, 2007