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what's your poison 

1. A query as to one's preference, specifically in regards to consummable goods
2. a query as to one's preference in alcoholic beverage or drugs
3. a question of one's preference in women
1. Alfred: What's your poison?
Rudyard: Give me a slice of pepperoni, beyotch!

2. Alfred: What's your poison?
Rudyard: Give me some mother fuckin' crack!

3. Alfred: What's your posion?
Rudyard: I likes me the big-titty bitches yo!
Alfred: Word!

what's your poison 

What are you drinking? Usually in terms of alcohol

What's Your Poison? 

An awesome podcast that talks about anything that makes people uncomfortable. Like awkward sex, brutal crimes, and anything taboo, all while drinking some sort of appropriate alcohol. Booze & Taboos.
-Have you heard the new episode of 'What's Your Poison?'
-No, why?
-She had to explain fisting to her grandmother!
What's Your Poison? by Moxology September 23, 2019

What's your poison, folks? 

used to ask someone what they would like to drink.
The bartender raised an eyebrow at the group and asked with a smirk, "What's your poison, folks? Whiskey, beer, or something more exotic?"

whats your poison? 

usually said by sleazy guys in bars as a way of asking to buy you a drink
"hey...What's Your Poison"
"baileys now feck off"
whats your poison? by Beaky February 29, 2004
Spidey sense for evading poop on the street, canine or otherwise.
When walking in NYC or LA, you need shitdar.
Shitdar by Sickomonster June 3, 2026
Word of the Day on June 6, 2026