look up any word, like pussy:
 
4.
1. Usually used to get an understanding of what someone is seeing. In most cases, the object in question is a face or an animal.
2. What people say when they just can't quite figure out what the hell their looking at.
Jesse: What's that?
Andy: My face.
by I Make Folks Cry August 22, 2011
 
1.
1. Another way of saying "what did you just say?", or asking the speaker to repeat their previous statement, due to lack of volume or attention or volume.
Synonyms: Huh? What? Whu? What did you say?, say again?, you talkin' to me? etc.

2. The question asked by youtube haters, cyber thugs, and internet toughguys when they first see a girl naked at age 45.
1. Matt: "I heard Dave knocked out Bruce last night and took his dope."
Vinnie: (paying attention to something else) "What's that?"
Matt: "I said, I heard Dave knocked out Bruce last night and took his dope."

2. (Paid-up-front-hooker removes her panties before youtube hater)
45 year old Youtube Hater (pointing to the snooch): What's that?
by BHK on Vernor April 22, 2009
 
2.
Something you say when you are embarrassed about something or trying to change the subject.
Adam: "So Dwain I heard you blew that guy last night."

Dwain: "What's that?"
by Brucist August 04, 2007
 
3.
Another way of saying "what?" or "pardon me"

Synonyms: what, pardon me, say that again, I beg your pardon, I'm sorry?
Person 1- (Says something unintelligible)
Person 2 - What's that?"
Person 1 - I said we should head back now.
Person 2- Oh, alright then
by scratchpiece January 22, 2011
 
5.
What is that
Yo, whatsthat
by Hercolena Oliver November 12, 2008
 
6.
as in, "what did you say?". sounds tough. Travis Bickle says it in Taxi Driver
Bob: Hey, Charlie.... you're a fucking douche bag
Charlie: What's that?
by Zak Hall February 05, 2005
 
7.
1. Overhang above fat above vagina
2. A question asked by a gay man who has never seen a vagina
Your what's that is hanging out.
by Ari Smell July 15, 2006