Top Definition
A general infection of the penis caused by a number of different factors. These can include through fornication; a lack of personal hygiene; infection caused by an injury; or a dodgy circumcision, as carried out on some parts of the developing world.

The word is used in a general sense in reference to any infection or suspected infection of the male genital area.
Man, I think that girl from the bar last night gave me wangrene.

A number of men in developing countries die from wangrene as a result of dirty surgical instruments used during circumcisions each year.

My wangrene has flared up again, and it won't stop itching.
by Wolfman21 September 20, 2010

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