To suddenly become unnecessarily worried, anxious, upset, or paranoid most often while under the influence of an intoxicating substance--especially marijuana.

Sometimes refers to a more favorable drug-induced mood change such as suddenly experiencing uncontrollable laughter, though the term "geek out" is more appropriate in this case.

to freak out, go crazy, or loose the mind.

To throw a huge fit

The feeling of mild depression and high anxiety when one has binged on large amounts of psychoactive substances, just as those substances, which had caused a high, where off. Usually the testy, easily annoyed, "bug-eyed" feeling brought about as stimulants such as cocaine or amphetamines leave one's system. One usually, to counteract the unpleasant wig out feeling, drinks large amounts of alcohol, smokes weed, or consumes larges amounts of anti-anxiety benzo pills like xanax.

To trip out or act in a strange/wierd way.

To throw a fit or go crazy, usually caused by something, but sometimes spontaneously caused by build up of energy.

Someone thowing a fit over things not important.