Top Definition
Surgical removal of the vaginal orifice. Should only be done by people who have terminally diseased/cancerous vaginas; not too be done by FTMs because vaginas are way comfier and better than penises.
Dr. Mendel: Sir, your wife is in horrible condition down there, I think we may have to perform a vaginectomy.

(Husband): NOOOOOOOO!!!!!!!
by JessieBird January 02, 2009
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