Top definition
a medical condition: When a man falls deeply inlove with the woman he loses his virginity to. This woman who holds the mans "v card" has complete control over him for a period of time.
Ever since Jon banged Kate hes been acting like a pussy whipped faggot. Havent seen him in weeks.

I know man, a bad case of V-Card Syndrome.
by davidnfld July 21, 2010
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