Tylenol 

A drug that cures your headache.

Son: “Mom I have a really bad headache.”

Mom “Okay I’ll get the Tylenol.”

Tylenol by HawaiianHotShot September 3, 2019

Tylenol 

North American brand of a painkiller whose active ingredient is acetaminophen (AKA paracetamol outside North America).

Don't take more than the recommended dose of this stuff (or of any other paracetamol/acetaminophen based painkillers). Overdose can cause liver failure, a fairly unpleasant way to die.

There are tales of people overdosing on tylenol/paracetamol pills one evening, and waking up the next morning feeling sheepish... they go about their business as normal, then later that afternoon start to feel really ill, get rushed to hospital and die shortly afterwards because their liver is knackered.

You really do *not* want to overdose on Tylenol/paracetamol. Trust me on this one.

Tylenol by Durban Ictionary April 21, 2007

Tylenol 

a headache that will most likely require the OTC drug of the same name

"All that talkin' is gon' give me a tylenol.." - Kanye West "Celebration"

Tylenol by Greg B. November 1, 2005

Tylenol 

A cough medicine, which in large doses, can cause a feeling of high. Due to the ingredient Cocomide.

Shut up and point me to the direction of your tylenol closet.

Tylenol by Little_Chris October 19, 2004

Tylenol 

However

However...he's such a Tylenol

Tylenol by Jaxie666 May 9, 2021

Tylenol 

A pain drug that has recently been named as the “reason for autism”, this is now slowly becoming slang for autism, saying someone ‘eats Tylenol’ is calling them autistic

Friend 1: I have an encyclopedic knowledge of My Little Pony.

Friend 2: Sure, Tylenol muncher.
Friend 1: Stfu I am not diagnosed

Tylenol by Robin_da_frog October 8, 2025

Tylenol 2

A combination of 300 mg acetaminophen, 15 mg caffeine, and 15 mg codeine.

CWE Tylenol 2s before you take recreational doses unless you wanna rape your liver.

Tylenol 2 by Qwertyuiopqwer July 10, 2016