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Similar to being ambidextrous, but instead of having another good hand, you have one less good hand: you have no good hands, and are incredibly clumsy as a result.
Benn: Dude, don't throw the ball to Dave he has two left hands!

Benn: Damn it Ron, you dropped the entire bag of popcorn.
Ron: Sorry man, I got two left hands.
by BennduR July 11, 2010