Top Definition
What happens when you post a funny, cool, winning or failing video using a tweet and you ask your friends to tweet back a witty caption for it.
You tweet:

"Watch this guy's nuts get hit by a potato gun and tell me what you think. #Twittershots"

And people respond:

"That tater gun makes sure that that guy never gets tots someday! #Twittershots"

"Mashed Balls! #Twittershots"

etc, etc..
by Spinaroonie June 02, 2011

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