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n. A word rightly used when referring to a twunt, dumb fuck, and/or cock-sucking-mother-fucking-God-damned-dick-licking-son-of-a-fucking-bitch-tit

*Please note, it is safe to use this word in public places. Especially, at the play ground around little children and there milfy moms.
"Oh my God! Your a twit hole! DON'T TALK TO ME!"
by PeNEz pUmp May 14, 2009
an asshole who posts annoying tweets on Twitter
I wonder what twitholes have to say about the economic recession.
by Nuclear5641 September 30, 2010